| 憤愢 挊彂 妛夛敪昞 |
丒Yuta Komori, Shun Sugimoto, Toranosuke Sato, Honoka Okawara, Ryo Watanabe,
Yuki Takano, Satoshi Kitaoka, Yuya Egawa, A new boron-rhodamine-containing
carboxylic acid as a sugar chemosensor, Sensors, 23(3): 1528 (2023). https://doi.org/10.3390/s23031528.
丒Yuji Doi, Daigo Wakana, Satoshi Kitaoka, Fumiaki Sato, Eiji Tanaka, Hisashi
Takeda, Tomoo Hosoe, Ergot alkaloids in sclerotia collected in Japan: synthetic
profiles and induction of apoptosis by Clavine-type compounds, J. Nat.
Med. (2023
丒Yuji Doi, Daigo Wakana, Satoshi Kitaoka,
Hisashi Takeda, Eiji Tanaka, Tomoo Hosoe, Secalonic acid and benzoic acid analogues
exhibiting cytotoxicity against cancer cells isolated from Claviceps
yanagawaensis, Adv. Microbiol., 12: 649-670 (2022).
丒Hinako Kikuchi, Yuki Nakamura, Chika Inoue, Sayaka Nojiri, Miho Koita,
Minori Kojima, Hiroki Koyama, Ryotaro Miki, Toshinobu Seki, and Yuya Egawa,
Hydrogen peroxide-triggered conversion of boronic acid-appended insulin
into insulin and its application as a glucose-responsive insulin formulation,
Mol. Pharm., 18: 4224-4230 (2021).
丒Ryotaro Miki, Tomoya Yamauchi, Kosuke Kawashima, Yuya Egawa, Toshinobu Seki, Multinuclear NMR study on the formation and polyol-induced deformation mechanisms of worm-like micelles composed of cetyltrimethylammonium bromide and 3-fluorophenylboronic acid, Langmuir, 37: 3438-3445 (2021).
丒Yuki Kobayashi, Yu Kojima, Ryotaro Miki, Toshinobu Seki, Yuya Egawa, Rotaxa-polymeric-gelation of acrylamides with vinyl-兝-cyclodextrin, J. Incl. Phenom. Macrocycl. Chem., 98: 43-48 (2020).
丒Jun Kurihara, Masaki Uchida, Tsutomu Yamaki, Tomomi Hatanaka, Toshinobu Seki, Hideshi Natsume, Effect of Hydrophilic Chain Length in Non-Ionic Surfactant on the Physicochemical Characteristics, Gene Expression Efficiency and Cytotoxicity of DNA/Poly-L-Ornithine/Niosome Ternary Complexes for Gene Delivery, J. Pharm. Sci. Technol., Jpn., 80, 156-161 (2020).
丒Yui Ohno, Tomohiro Seki, Yu Kojima, Ryotaro Miki, Yuya Egawa, Osamu Hosoya, Keizo Kasono, Toshinobu Seki, Investigation of factors that cause insulin precipitation and/or amyloid formation in insulin formulations, J. Pharm. Health Care Sci., 5: 22 (2019).
丒Yui Ohno, Momoko Kawakami, Tomohiro Seki, Ryotaro Miki, Toshinobu Seki, Yuya Egawa,
Cell adhesive character of phenylboronic acid-modified insulin and its potential as long-acting insulin,
Pharmaceuticals, 12: 121 (2019).
丒Yuki Kobayashi, Yu Kojima, Ryotaro Miki, Toshinobu Seki, Takashi Fujihara, Yoshihiro Ishimaru, and Yuya Egawa,
Single-step preparation of topological gels using vinyl-modified 兝-cyclodextrin as a figure-of-six cross-linker,
J. Incl. Phenom. Macrocycl. Chem., 92: 311-317 (2018).
丒Chihiro Takei, Yui Ohno, Tomohiro Seki, Ryotaro Miki, Toshinobu Seki, Yuya Egawa,
Sugar-Responsive Layer-by-Layer Film Composed of Phenylboronic Acid-Appended Insulin and Poly(vinyl alcohol),
Chem. Pharm. Bull., 66: 368-374 (2018).
丒Ryotaro Miki, Chihiro Takei, Yasushi Ohtani, Kosuke Kawashima, Ayaka Yoshida, Yu Kojima, Yuya Egawa, Toshinobu Seki, Daisuke Iohara, Makoto Anraku, Fumitoshi Hirayama, and Kaneto Uekama,
Glucose Responsive Rheological Change and Drug Release from a Novel Worm-like Micelle Gel Formed in Cetyltrimethylammonium Bromide/Phenylboronic Acid/Water System,
Mol. Pharm., 15:1097-1104 (2018).
丒Ryotaro Miki, Yuuichi Hara, Nahomi Imai, Masahiro Sugino, Yuya Egawa, Osamu Hosoya, Kazuhiko Juni, Toshinobu Seki,
A study on an in vitro changeable pH dissolution/permeation system that reflects pH shifts of the gastrointestinal tract: a case of a poorly soluble basic drug,
AATEX, 22:107-114 (2017).
丒Wataru Uchida, Maiki Yoshikawa, Tomohiro Seki, Ryotaro Miki, Toshinobu Seki, Takashi Fujihara, Yoshihiro Ishimaru, Yuya Egawa,
A polyrotaxane gel using boronic acid-appended 兞-cyclodextrin as a hybrid cross-linker,
J. Incl. Phenom. Macrocycl. Chem., 89: 281-288 (2017).
丒Yutaro Hazama, Wataru Uchida, Toshihisa Maekawa, Ryotaro Miki, Shinji Oshima, Yuya Egawa, Osamu Hosoya, Toshinobu Seki,
Preclinical Study of Tacrolimus Ointment for Prevention of Its Systemic Absorption in Atopic Dermatitis Model Mice According to Their Skin Conditions,
Jpn. J. Pharm. Health Care Sci., 43: 477-491 (2017).
丒Yu Kojima, Tomoyuki Okano, Tomohiro Seki, Misato Namiki, Yuya Egawa, Ryotaro Miki, Kazuhiko Juni, Toshinobu Seki,
Polyol-responsive pseudopolyrotaxanes based on phenylboronic acid-modified polyethylene glycol and cyclodextrins,
J. Incl. Phenom. Macrocycl. Chem., 87:295-303 (2017).
丒Ryotaro Miki, Yuki Kobayashi, Yuko Nakamura, Tomoko Asaka, Nahomi Imai, Yuka Hirayama, Osamu Hosoya, Yuya Egawa, Toshinobu Seki,
The development of a novel in vitro gastrointestinal absorption model comprising drug dissolution/migration/permeation processes: interactions between a drug and an excipient,
AATEX, 21:1-13 (2016).
丒Tomohiro Seki, Keigo Abe, Yuya Egawa, Ryotaro Miki, Kazuhiko Juni, Toshinobu Seki,
A pseudopolyrotaxane for glucose-responsive insulin release: The effect of binding ability and spatial arrangement of phenylboronic acid group,
Mol. Pharmaceutics, 13:3807-3815 (2016).
丒Naoki Shimomura, Yuya Egawa, Ryotaro Miki, Takashi Fujihara, Yoshihiro Ishimaru, Toshinobu Seki,
Red fluorophore comprising of a borinate-containing xanthene analogue as a polyol sensor,
Org. Biomol. Chem., 14:10031-10036 (2016).
丒Yutaro Hazama, Toshihisa Maekawa, Ryotaro Miki, Shinji Osima, Yuya Egawa, Kazuhiro Morimoto, Toshinobu Seki,
Effect of physiological changes in the skin on systemic absorption of tacrolimus following topical application in rats,
Biol. Pharm. Bull., 39:343-352 (2016).
丒Keisuke Suwa, Munenari Nagasaka, Satoshi Niina, Yuya Egawa, Toshinobu
Seki, Jun-ichi Anzai,Sugar-response of layer-by-layer films composed of
poly(vinyl alcohol) and poly(amidoamine) dendrimer bearing 4-carboxyphenylboronic
acid,
Colloid and Polymer Science, 293:1043-1048 (2015).
丒Tomohiro Seki, Keigo Abe, Kiminobu Nakamura, Yuya Egawa, Ryotaro Miki,
Kazuhiko Juni,Toshinobu Seki,Sugar-responsive pseudopolyrotaxanes and their
application in sugar-induced release of PEGylated insulin,
J. Incl. Phenom. Macrocycl. Chem., 82:417-424 (2015).
丒Tomohiro Seki, Misato Namiki, Yuya Egawa, Ryotaro Miki, Kazuhiko Juni, Toshinobu Seki, Sugar-Responsive Pseudopolyrotaxane Composed of Phenylboronic Acid-Modified Polyethylene Glycol and
兞-Cyclodextrin,
Materials, 8: 1341-1349 (2015)
丒Ryotaro Miki, Yasuna Ichitsuka, Takumi Yamada, Soichiro Kimura, Yuya Egawa, Toshinobu Seki, Kazuhiko Juni, Hideo Ueda, Yasunori Morimoto,
Development of a membrane impregnated with a poly(dimethylsiloxane)/poly(ethylene glycol) copolymer for a high-throughput screening of the permeability of drugs, cosmetics, and other chemicals across the human skin,
Eur. J. Pharm. Sci., 66: 41-49 (2015)
丒Katsunori Shinohara, Miki Yamashita, Wataru Uchida, Shinji Oshima, Yuya Egawa, Ryotaro Miki, Osamu Hosoya, Tohru Kishino, Toshinobu Seki, Kazuhiko Juni,
Preparation of polypseudorotaxanes composed of cyclodextrin and polymers in microspheres,
Chem. Pharm. Bull., 62: 962-966 (2014)
丒Yamaki T, Kamiya Y, Ohtake K, Uchida M, Seki T, Ueda H, Kobayashi J, Morimoto Y, Natsume H,
A Mechanism Enhancing Macromolecule Transport Through Paracellular Spaces Induced by Poly-L-Arginine: Poly-L-Arginine Induces the Internalization of Tight Junction Proteins via Clathrin-Mediated Endocytosis,
Pharm Res, 31: 2287-2296 (2014)
丒Ryota Watahiki, Katsuhiko Sato, Keisuke Suwa, Satoshi Niina, Yuya Egawa, Toshinobu Seki, Jun-ichi Anzai,
Multilayer films composed of phenylboronic acidmodified dendrimers sensitive to glucose under physiological conditions,
J. Mater. Chem. B, 2: 5809-5817 (2014)
丒Kiminobu Nakamura, Tomohiro Seki, Yuya Egawa, Ryotaro Miki, Yoshiki Oda, Takashi Yamanoi and Toshinobu Seki,
Sugar-Sensitive Supramolecular Structures Based on Phenylboronic Acid-Modified Cyclodextrins,
Chem. Pharm. Bull., 61: 1188-1191 (2013)
丒Toshinobu Seki, Airi Hamada, Yuya Egawa, Tsutomu Yamaki, Masaki Uchida, Hideshi Natsume, Soichiro Kimura and Hideo Ueda,
Evaluation of the Effects of Absorption Enhancers on Caco-2 Cell Monorayers by Using a Pore Permeation Model Involving Two Defferent Sizes,
Biol. Pharm. Bull., 36: 1862-1866 (2013)
丒Takahiro Rikita, Yuya Egawa, Toshinobu Seki,
Fluorometric determination of inulin using 5-quinolineboronic acid and inulinase,
Anal. Biochem., 426: 24-26 (2012)
丒Shinji Oshima, Chihiro Suzuki, Rina Yajima, Yuya Egawa, Osamu Hosoya, Kazuhiko Juni, Toshinobu Seki,
The use of an artificial skin model to study transdermal absorption of drugs in inflamed skin,
Biol. Pharm. Bull., 35: 203-209 (2012)
丒Toshinobu Seki, Nanako Fukushi, Hiroto Maru, Soichiro Kimura, Sumio Chono, Yuya Egawa, Kazuhiro Morimoto, Hideo Ueda, Yasunori, Morimoto,
Effects of sperminated pullulans on the pulmonary absorption of insulin,
Yakugaku Zasshi, 131: 307-314 (2011)
丒Soichiro Kimura, Kaori Miyazaki, Ryotaro Miki, Takeshi Shimamura, Sachihiko Numajiri, Toshinobu Seki, Kazuhiko Juni, Hiromi Kitano, Hideo Ueda, Yasunori Morimoto,
Evaluation of an artificial polymer membrane as a human skin alternative membrane available for formulation tests of transdermal products,
J. Pharm. Sci. Technol. Jpn., 71(3), 191- 196 (2011)
丒Masaki Uchida, Hideshi Natsume, Toshinobu Seki, Tateki Uchida, Yasunori Morimoto,
Relationship between the particle velocity and introduction of drug-loaded microparticles into the skin in a microparticulate bombardment system,
Chem. Pharm. Bull., 59(5), 662-665 (2011)
丒Toshinobu Seki, Takaaki Kiuchi, Hiroki Seto, Soichiro Kimura, Yuya Egawa, Hideo Ueda, Yasunori Morimoto,
Analysis of the rat skin permeation of hydrophilic compounds using the Renkin function,
Biol. Pharm. Bull., 33: 1915-1918 (2010)
丒Shinji Oshima, Tatsuya Sashida, Yuya Egawa, Osamu Hosoya, Kazuhiko Juni, Toshinobu Seki,
Study of a drug interaction involving the permeation process using an artificial skin model as an alternative to animal skin,
AATEX, 15: 97-105 (2010)
丒Yuya Egawa, Yoshiyuki Tanaka, Ryota Gotoh, Satoshi Niina, Yu Kojima, Naoki Shimomura, Hiroko Nakagawa, Toshinobu Seki, Jun-ichi Anzai,
Nitrogen-15 NMR spectroscopy of sugar sensor with B-N interaction as a key regulator of colorimetric signals,
Chem. Lett., 39: 1188-1189 (2010)
丒Ryotaro Miki, Soichiro Kimura, Hideo Ueda, Takeshi Shimamura, Sachihiko Numajiri, Toshinobu Seki, Kazuhiko Juni, Hiromi Kitano, Yasunori Morimoto,
Suitability of synthetic copolymer membranes as a human skin alternative for in vitro skin permeation testing,
AATEX, 15: 14-27 (2010)
丒Kohei Togami, Sumio Chono, Toshinobu Seki, Kazuhiro Morimoto,
Aerosol-based efficient delivery of telithromycin, a ketolide antimicrobial agent, to lung epithelial lining fluid and alveolar macrophages for treatment of respiratory infections,
Drug Dev. Ind. Pharm., 36: 861-866 (2010)
丒Kohei Togami, Sumio Chono, Toshinobu Seki, Kazuhiro Morimoto,
Intracellular pharmacokinetics of telithromycin, a ketolide antibiotic, in alveolar macrophages,
J. Pharm. Pharmacol., 62, 71-75 (2010)
丒Kohei Togami, Sumio Chono, Toshinobu Seki, Kazuhiro Morimoto,
Distribution characteristics of telithromycin, a novel ketolide antimicrobial agent applied for treatment of respiratory infection, in lung epithelial lining fluid and alveolar macrophages,
Drug Metab. Pharmacokinet., 24, 411-417 (2009)
丒Toshinobu Seki, Osamu Hosaya, Hideshi Natsume, Izumi Sato, Yuya Egawa, Hiroko Nakagawa, Kazuhiko Juni, Yasunori Morimoto,
Application of the Renkin function to characterize paracellular pathways in the nasal absorption of FITC-dextrans in rats,
J. Drug Del. Sci. Tech., 19, 331-335 (2009)
丒Sumio Chono, Rie Fukuchi, Toshinobu Seki, Kazuhiro Morimoto,
Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary insulin delivery,
J. Control. Release, 137, 104-109 (2009)
丒戝栰丂桾徍丄壀嶈岝梞丄嶗堜丂岝堦丄娭丂弐挩丄懞忋丂旤曚丄憗惃丂怢惓丄搰怷丂旤岝丄孲丂廋摽丄嵅摗丂廳堦丄搉曈丂堦峅丄搉曈丂懽桾丄憗悾丂岾弐丄巗尨丂榓晇丄
夘岇丒梴岇巤愝偵偍偗傞俀擭師妛惗傪懳徾偲偟偨懱尡宆妛廗偺幚巤偲昡壙乗抧堟堛椕傊峷專偡傞堛椕恖偺梴惉傪栚巜偟偰乗丄
幮夛栻妛丄27, 27-31 (2009)
丒Hideo Ueda, Mizue Mutoh, Toshinobu Seki, Daisuke Kobayashi, Yasunori Morimoto,
Acoustic cavitation as an enhancing mechanism of low-frequency sonophoresis for transdermal drug delivery,
Biol. Pharm. Bull., 32, 916-920 (2009)
丒Yuya Egawa, Ryota Gotoh, Toshinobu Seki and Jun-ichi Anzai,
Sugar response of boronic acid-substituted azobenzene dye-modified polymer,
Mater. Sci. Eng. C, 29, 115-118 (2009)
丒Toshinobu Seki, Nanako Fukushi, Sumio Chono, Kazuhiro Morimoto,
Effects of sperminated polymers on the pulmonary absorption of insulin,
J. Control. Release, 125, 246-251 (2008)
丒Kazuhiro Morimoto, Sumio Chono, Tadashi Kosai, Toshinobu Seki,
Design of cationic microspheres based on aminated gelatin for controlled release of peptide and protein drugs,
Drug Delivery, 15, 113-117 (2008)
丒Kazuhiro Morimoto, Nanako Fukushi, Sumio Chono, Toshinobu Seki,
Yasuhiko Tabata, Sperminated dextran, a cationized poltmer, as absorption enhancer for pulmonary application of peptide drugs,
Pharmazie, 63, 180-184 (2008)
丒Sumio Chono, Tomoharu Tanino, Toshinobu Seki, Kazuhiro Morimoto,
Efficient drug targeting to rat alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into mannosylated liposomes for treatment of respiratory intracellular parasitic infections,
J. Control. Release, 127, 50-58 (2008)
丒Sumio Chono, Tomoharu Tanino, Toshinobu Seki, Kazuhiro Morimoto,
Efficient drug delivery to alveolar macrophages and lung epithelial lining fluid following pulmonary administration of liposomal ciprofloxacin in rats with pneumonia and estimation of its antibacterial effects,
Drug Dev. Ind. Pharm., 34, 1090-1096 (2008)
丒Yuya Egawa, Ryosuke Hayashida, Toshinobu Seki and Jun-ichi Anzai,
Fluorometric determination of heparin based on self-quenching of fluorescein-labeled protamine,
Talanta, 76, 736-741 (2008)
丒Yuya Egawa, Tomohiro Seki, Ryotaro Miki, Toshinobu Seki,
Sugar-responsive smart materials based on phenylboronic acid and cyclodextrin,
J. Incl. Phenom. Macrocycl. Chem., 94: 1-10 (2019)
丒嶰栘 椓懢榊,
僼僃僯儖儃儘儞巁傪梡偄偨僌儖僐乕僗墳摎惈怴婯昍忬儈僙儖僎儖偺挷惢偲栻暔曻弌摿惈,
僆儗僆僒僀僄儞僗丄19, 5-11 (2019)
丒峕愳 桽嵠,
摐墳摎惈暘巕儅僔儞偵傛傞僀儞僗儕儞僐儞僩儘乕儖僪儕儕乕僗,
栻嵻妛丄77, 242-247 (2017)
丒Yuya Egawa, Ryotaro Miki, Toshinobu Seki,
Colorimetric Sugar Sensing Using Boronic Acid-Substituted Azobenzenes,
Materials, 7: 1201-1220 (2014)
丒峕愳丂桽嵠,丂娭丂弐挩丄
摐墳摎惈僀儞僗儕儞儕儕乕僗僔僗僥儉傪巜岦偟偨挻暘巕僫僲儅僔儞丄
栻妛嶨帍丄133, 1287-1295丂(2013)
丒娭丂弐挩丄
乬僔儕乕僘丂尋媶幰偵暦偔宱旂媧廂丂恖岺崅暘巕枌傪梡偄偨宱旂媧廂偺幚尡偵偮偄偰乭丄
COSME TECH JAPAN丄 10, 41-46 (2013)
丒娭丂弐挩丄
僀儞僗儕儞偺宱旲僨儕僶儕乕偵娭偡傞婎慴揑尋媶丄
栻妛嶨帍丄132, 1255-1262 (2012)
丒Yuya Egawa, Toshinobu Seki, Shigehiro Takahashi, Jun-ichi Anzai,
Electrochemical and optical sugar sensors based on phenylboronic acid and its derivatives,
Mater. Sci. Eng. C, 31, 1257-1264 (2011)
丒娭丂弐挩丄
僇僠僆儞惈崅暘巕傪梡偄偨僀儞僗儕儞偺擲枌媧廂懀恑丄
栻妛嶨帍丄130丗 1115-1121 (2010)
丒娭丂弐挩丄
堛椕偺僯乕僘傪傆傑偊偨宱旂媧廂嵻乮慡恎惈乯偺張曽愝寁丄
PHARM STAGE丄10: 25-28 (2010)
丒Yuya Egawa, Toshinobu Seki,
Related Topic: Cyclodextrin.乬Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds乭,
Springer Japan, Tokyo, pp.233-239 (2017)
丒Toshinobu Seki, Ryotaro Miki,
Related Topic: Measurement of Diffusion Coefficient of Chemicals.乬Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds乭,
Springer Japan, Tokyo, pp.377-384 (2017)
丒娭丂弐挩丂曇挊丄
乬PRACTICAL婎慴壔妛乭丄
嫗搒淎愳彂揦丄嫗搒(2015)
丒娭丂弐挩丄嶰栘丂椓懢榊丄
乬俢俢俽惢嵻偺奐敪丒昡壙偲幚梡壔庤朄乭丄
埨曐岞夘曇丄媄弍忣曬嫤夛(搶嫗) 丄p. 110-114 (2013)
丒娭丂弐挩乮懠乯丄
傒偰傢偐傞栻妛丂恾夝栻嵻妛丂夵掶俆斉丄
撿嶳摪丄搶嫗丄pp 3-94 (2012)
丒娭丂弐挩丄怷杮堦梞丄
乬儁僾僠僪丒僞儞僷僋惈堛栻昳偺怴婯DDS惢嵻偺奐敪偲墳梡乭丄
嶳杮丂徆曇丄儊僨傿僇儖僪僁 (戝嶃) 丄p. 178-184 (2011)
丒娭丂弐挩乮懠乯丄
乽怴偟偄恾夝栻嵻妛乿夵掶係斉丄
撿嶳摪丄p. 3-92 (2009)
丒嶳嶈 惞恗丄嶰栘 椓懢榊丄峕愳 桽嵠丄娭 弐挩丄僕儃儘儞巁桿摫懱/億儕價僯儖傾儖僐乕儖偵傛傞 擲抏惈宯偺摐墳摎惈儗僆儘僕乕摿惈丄擔杮栻妛夛 戞140擭夛丄2020擭3寧25乣28擔丄嫗搒
丒嶳撪 抦栫丄嶰栘 椓懢榊丄峕愳 桽嵠丄娭 弐挩丄廘壔僙僠儖僩儕儊僠儖傾儞儌僯僂儉/3-僼儖僆儘 僼僃僯儖儃儘儞巁偐傜側傞昍忬儈僙儖僎儖偺僌儖僐乕僗嫟懚偵傛傞曵夡儊僇僯僘儉夝柧偵岦偗偨 懡妀NMR夝愅丄擔杮栻妛夛 戞140擭夛丄2020擭3寧25乣28擔丄嫗搒
丒媏抧 梲壴巕丄拞懞 桪婫丄嶰栘 椓懢榊丄娭 弐挩丄峕愳 桽嵠丄夁巁壔悈慺偱妶惈壔偡傞僀儞僗儕 儞桿摫懱偺奐敪偲摐墳摎惈僀儞僗儕儞惢嵻傊偺壜擻惈丄擔杮栻妛夛 戞140擭夛丄2020擭3寧25 乣28擔丄嫗搒
丒戝栰 桼埶丄娭 抭岹丄彫搰 桾丄嶰栘 椓懢榊丄嵶扟 帯丄峕愳 桽嵠丄塅榓揷 婱擵丄壛墍 宐嶰丄 娭 弐挩丄慄堐壔僀儞僗儕儞搳梌晹埵偱偺栻暔媧廂惈偺夝愅丄戞140夞擔杮栻妛夛擭夛丄2020擭 3寧25擔乣28擔丄嫗搒
丒嶰栘 椓懢榊丄峕愳 桽嵠丄娭 弐挩
僌儖僐乕僗墳摎惈怴婯昍忬儈僙儖僎儖偺挷惢偲栻暔曻弌摿惈
丒嶰栘 椓懢榊丄扟揷晹 崄丄峕愳 桽嵠丄娭 弐挩
僇僠僆儞惈奅柺妶惈嵻/僼僃僯儖儃儘儞巁崿崌宯偵偍偗傞暘巕廤崌懱宍惉偲摐専弌傊偺墳梡
丒峕愳 桽嵠丄拞懞 桪婫丄嶰栘 椓懢榊丄娭 弐挩
僼僃僯儖儃儘儞巁廋忺僀儞僗儕儞丄僌儖僐乕僗僆僉僔僟乕僛丄兞-僔僋儘僨僉僗僩儕儞崿崌宯偵傛傞寣摐抣墳摎惈僀儞僗儕儞惢嵻
丒嶰栘 椓懢榊丄墫栰 偝傗偐丄嶳嶈 惞恗丄峕愳 桽嵠丄娭 弐挩
廘壔僙僠儖僩儕儊僠儖傾儞儌僯僂儉/3-僼儖僆儘僼僃僯儖儃儘儞巁崿崌宯拞偺暘巕廤崌懱峔憿偺夝柧偵岦偗偨儗僆儘僕乕摿惈挷嵏
丒彫嶳 寢惗丄拞懞 桪婫丄摗堜 旤斂丄嶰栘 椓懢榊丄娭 弐挩丄峕愳 桽嵠
僌儖僐乕僗偱曵夡偟僀儞僗儕儞桿摫懱傪曻弌偡傞岎屳椵愊枌偺嶌惢
丒嶰栘 椓懢榊丄媑揷 埢壺丄晲堜 愮栱丄峕愳 桽嵠丄娭 弐挩
摐墳摎惈昍忬儈僙儖僎儖偐傜偺僌儖僐乕僗埶懚揑栻暔曻弌惈
丒嶰栘 椓懢榊丄愳搱 峃夘丄墫栰 偝傗偐丄峕愳桽嵠丄娭 弐挩
惗棟揑 pH 偵偍偗傞摐墳摎惈昍忬儈僙儖偺挷惢偍傛傃儗僆儘僕乕摿惈偺昡壙
丒峕愳 桽嵠丄撪揷 榡丄嶰栘 椓懢榊丄娭 弐挩
僼僃僯儖儃儘儞巁廋忺兞-CyD 偲億儕價僯儖傾儖僐乕儖偐傜側傞僌儖僐乕僗僆僉僔僟乕僛娷桳摐墳摎惈僴僀僪儘僎儖
丒彫椦 桼婓丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
價僯儖婎廋忺CyD偲奺庬價僯儖儌僲儅乕偺嫟廳崌偵傛傞婡擻惈僎儖偺儚儞億僢僩挷惢偲偦偺暔惈昡壙
丒楅栘 婱戝丄嶰栘 椓懢榊丄峕愳 桽嵠丄娭 弐挩
僌儖僐乕僗儌僯僞儕儞僌偵岦偗偨儃儕儞巁桿摫懱寀岝儌僲儅乕偺崌惉偲崅暘巕嵽椏傊偺摫擖
丒彫椦 桼婓丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
DDS 婎嵻偲偟偰墳梡壜擻側價僯儖婎廋忺僔僋儘僨僉僗僩儕儞偲奺庬儌僲儅乕偺嫟廳崌偵傛傞僗儔僀僪儕儞僌僎儖偺挷惢
丒Yuki Kobayashi, Yuya Egawa, Ryotaro Miki, Toshinobu Seki
One-Pot Preparation of Slide-Ring Gels Using A Vinyl-Modified Cyclodextrin and Vinyl-Based Monomers
丒愳懞丂抦桾丄戝栰丂桼埶丄嶰栘丂椓懢榊丄峕愳丂桽嵠丄娭丂弐挩
僼僃僯儖儃儘儞巁廋忺僀儞僗儕儞偺傾儈儘僀僪宍惉梷惂梫場偺挷嵏
丒Yuki Kobayashi,Yuya Egawa,Ryotaro Miki,Toshinobu Seki,
One-Pot Preparation of Slide-Ring Gels Using a Vinyl-Modified Cyclodextrin.
丒Yuya Egawa,Ryotaro Miki,Toshinobu Seki,
Sugar Responsive Molecular Machines based on the Combination of Phenylboronic Acid and Cyclodextrins.
丒楅栘 岲恀丄彫椦 桼婓丄彫搰 桾丄嶰栘 椓懢榊丄娭 弐挩丄峕愳 桽嵠
價僯儖婎廋忺 兞-僔僋儘僨僉僗僩儕儞偲 N-僀僜僾儘僺儖傾僋儕儖傾儈僪傪梡偄偨僗儔僀僪儕儞僌壦嫶僎儖偺挷惢
丒媣曐揷 椇隳丄彫椦 桼婓丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
僽儘僢僋嫟廳崌懱偲僔僋儘僨僉僗僩儕儞偐傜宍惉偝傟傞暋崌棻巕偵娭偡傞尋媶
丒媑揷 埢壺丄晲堜 愮栱丄嶰栘 椓懢榊丄峕愳 桽嵠丄娭 弐挩
儅僀僋儘僒僀僘偺僼儘乕僗儖乕僙儖傪梡偄偨昍忬儈僙儖僎儖偐傜偺摐墳摎惈栻暔曻弌偺昡壙
丒晲堜 愮栱丄媑揷 埢壺丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
儃儘儞巁廋忺僀儞僗儕儞偲億儕價僯儖傾儖僐乕儖偐傜側傞摐墳摎惈僎儖偺挷惢
丒彫椦 桼婓丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
價僯儖婎廋忺僔僋儘僨僉僗僩儕儞偲奺庬儌僲儅乕偺嫟廳崌偵傛傞僗儔僀僪儕儞僌僎儖偺儚儞億僢僩挷惢偲偦偺暔惈昡壙
丒戝栰 桼埶丄愳懞 抦桾丄嶰栘 椓懢榊丄峕愳 桽嵠丄悪栰 夒峗丄嵶扟 帯丄娭 弐挩
僀儞僗儕儞桼棃傾儈儘僀僪乕僔僗傪夞旔壜擻側怴婯僀儞僗儕儞桿摫懱
丒尨 桾堦丄戝栰 夒搇丄曅娸 岝暯丄墫扟 桬搊丄揷拞 椚丄徏塱 廏弔丄悪栰 夒峗丄嶰栘 椓懢榊丄嵶扟 帯丄峕愳 桽嵠丄渘擇 榓旻丄娭 弐挩
堓彎奞偵傛傞堓攔弌偺曄壔偲偦傟偵傛傞栻暔媧廂惈傊偺塭嬁
丒峕愳 桽嵠
儂僂慺壔崌暔傪梡偄偨摐僙儞僒乕偍傛傃摐墳摎惈僪儔僢僌僨儕僶儕乕僔僗僥儉偺奐敪
丒戝栰 桼埶丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
摐嵔偲偺憡屳嶌梡偵婎偯偔帩懕嶌梡傪帵偡儃儘儞巁廋忺僀儞僗儕儞
丒嶰栘 椓懢榊丄戝扟 懽巎丄峕愳 桽嵠丄娭 弐挩丄埩尨 戝曘丄埨妝 惤丄暯嶳 暥弐丄忋姌 寭恖
儃儘儞巁娷桳昍忬儈僙儖僎儖偺僌儖僐乕僗偵傛傞儗僆儘僕乕摿惈偺曄壔
丒彫椦 桼婓丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
價僯儖婎廋忺 CyD 偲僀僜僾儗儞偺廳崌偵傛傞僗儔僀僪儕儞僌僎儖偺儚儞億僢僩挷惢偲暔惈昡壙
丒撪揷 榡丄媑愳 崃堐庽丄娭 抭岹丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
僼僃僯儖儃儘儞巁廋忺 g-CyD 偵傛傞曪愙暋崌懱偲壔妛寢崌摨帪宍惉偐傜側傞僴僀僪儘僎儖偺挷惢偲偦偺摐墳摎惈栻暔曻弌傊偺棙梡
丒晲堜 愮栱丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
儃儘儞巁廋忺僀儞僗儕儞傪梡偄偨摐墳摎惈岎屳椵愊枌
丒彫椦 桼婓丄彫搰 桾丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
價僯儖-僔僋儘僨僉僗僩儕儞傪梡偄偨僗儔僀僪儕儞僌僎儖偺儚儞億僢僩挷惢
丒戝栰 桼埶丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
儃儘儞巁廋忺僀儞僗儕儞偲摐嵔偺憡屳嶌梡傪棙梡偟偨寣娗撪彊曻壔偺帋傒
丒撪揷 榡丄媑愳 崃堐庽丄娭 抭岹丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
億儕價僯儖傾儖僐乕儖偲僼僃僯儖儃儘儞巁廋忺兞-僔僋儘僨僉僗僩儕儞偐傜側傞僴僀僪儘僎儖偐傜偺摐墳摎惈栻暔曻弌
丒尨 桾堦丄悪栰 夒峗丄嶰栘 椓懢榊丄嵶扟 帯丄渘擇 榓旻丄娭 弐挩
堓捵釃儌僨儖儔僢僩偵偍偗傞栻暔媧廂偵娭偡傞尋媶
丒彫搰 桾丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
壦嫶晹偵億儕儘僞僉僒儞峔憿傪桳偡傞僼僃僯儖儃儘儞巁廋忺僎儖偺挷惢偲摐墳摎惈偺昡壙
丒壓懞 桳婸丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
寀岝惈儃儕儞巁桿摫懱 (JoSai-Red) 偺夁巁壔悈慺墳摎媦傃僌儖僐乕僗僙儞僒乕傊偺墳梡
丒晲堜 愮栱丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
億儕儃儘儞巁偲億儕價僯儖傾儖僐乕儖傪慻傒崌傢偣偨僸僪儘僎儖偺挷惢偲摐墳摎惈嫇摦偺昡壙
丒揷拞 梇栫丄慜愳 弐媣丄娫 桽懢楴丄嶰栘 椓懢榊丄峕愳 桽嵠丄娭 弐挩
儅僀僋儘僟僀傾儕僔僗朄偵傛傞旂晢拞僞僋儘儕儉僗擹搙偺怴婯應掕朄偵娭偡傞専摙
丒峕愳 桽嵠
僀儞僗儕儞僨儕僶儕乕僔僗僥儉傪巜岦偟偨儃儘儞巁廋忺僔僋儘僨僉僗僩儕儞偵傛傞摐墳摎惈挻暘巕峔憿
丒撪揷 榡丄 媑愳 崃堐庽丄 娭 抭岹丄 峕愳 桽嵠丄 嶰栘 椓懢榊丄 娭 弐挩
僼僃僯儖儃儘儞巁廋忺 g-CyD偲億儕價僯儖傾儖僐乕儖偵傛傞摐墳摎惈億儕儘僞僉僒儞僕僢僷乕
丒彫搰 桾丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
壦嫶揰偵儘僞僉僒儞峔憿傪桳偡傞摐墳摎惈僎儖偺挷惢偲孞傝曉偟墳摎惈偺昡壙
丒壓懞 桳婸丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
億儕僆乕儖壔崌暔傪擣幆偡傞儃儕儞巁桿摫懱偺寀岝曄壔儊僇僯僘儉偺夝柧
丒Yuki Kobayashi, Yuya Egawa, Ryotaro Miki, Toshinobu Seki,
The effect of cyclodextrins on the formation of microparticles composed of a block copolymer, polypropylene glycol and polycaprolactone.
丒惎栰 弮婱丄楅栘 婱戝丄彫搰 桾丄嶰栘 椓懢榊丄峕愳 桽嵠丄娭 弐挩
堎側傞壓尷椪奅梟夝壏搙傪桳偡傞億儕儅乕傪慻傒崌傢偣偨僽儘僢僋僐億儕儅乕偺挷惢偲偦偺暘巕廤崌懱偺壏搙墳摎惈偺昡壙
丒慜愳 弐媣丄娫 桽懢楴丄撪揷 榡丄晲堜 愮栱丄彫椦 桼婓丄嶰栘 椓懢榊丄戝搰 怴巌丄峕愳 桽嵠丄娭 弐挩
僞僋儘儕儉僗旂晢揔梡屻偺慡恎堏峴惈偲嬊強懾棷惈偺儔僢僩傪梡偄偨昡壙
丒娫丂桽懢楴丄撪揷丂榡丄慜愳丂弐媣, 嶰栘丂椓懢榊丄戝搰丂怴巌丄峕愳丂桽嵠丄娭丂弐挩
傾僩僺乕惈旂晢墛儌僨儖儅僂僗傪梡偄偨僞僋儘儕儉僗擃峱旂晢揔梡屻偺慡恎偍傛傃旂晢嬊強堏峴惈偵媦傏偡旂晢忬懺偺塭嬁
丒暯嶳 桰壴丄嶰栘 椓懢榊丄峕愳 桽嵠丄娭 弐挩
梟弌/堏摦/媧廂偺夁掱傪楢懕揑偵昡壙偡傞in vitro徚壔娗媧廂儌僨儖偵娭偡傞専摙乗栻暔偲怘昳惉暘偺憡屳嶌梡乗
丒寭巕 愮嶇搒丄壓懞 桳婸丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
僿僾僞儊僠儞僔傾僯儞傪婎杮崪奿偲偟偨儃儘儞巁娷桳嬤愒奜摐墳摎惈僾儘乕僽
丒烴堜 朑巕丄壓懞 桳婸丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
儃儘儞巁偲傾僝婎偺憡屳嶌梡偵婎偯偔寀岝摐壔妛僙儞僒乕
丒撪揷 榡丄嶰栘 椓懢榊丄峕愳 桽嵠丄娭 弐挩
億儕儘僞僉僒儞峔憿傪棙梡偟偨怴婯栻暔扴懱挷惢偺帋傒
丒彫搰 桾丄晲堜 愮栱丄娭 抭岹丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
壦嫶揰偵儘僞僉僒儞峔憿傪帩偪摐偵孞傝曉偟墳摎偡傞僎儖偺挷惢
丒戝扟 懽巎丄嶰栘 椓懢榊丄峕愳 桽嵠丄娭 弐挩丄埩尨 戝曘丄暯嶳 暥弐丄忋姌 寭恖
廘壔僙僠儖僩儕儊僠儖傾儞儌僯僂儉/僼僃僯儖儃儘儞巁/悈宯偺昍忬儈僙儖僎儖偺宍惉偲pH偺娭學偵偮偄偰偺峫嶡
丒慜愳丂弐媣丄娫丂桽懢楴丄嶰栘丂椓懢榊丄戝搰丂怴巌丄峕愳丂桽嵠丄娭丂弐挩
僞僋儘儕儉僗旂晢揔梡屻偺慡恎堏峴惈偵媦傏偡旂晢忬懺偺曄壔偲寣娗廂弅栻偺塭嬁
丒嶰栘丂椓懢榊丄峕愳丂桽嵠丄娭丂弐挩丄埩尨丂戝曘丄暯嶳丂暥弐丄忋姌丂寭恖
摐偵墳摎偟偰擲惈偑曄壔偡傞廘壔僙僠儖僩儕儊僠儖傾儞儌僯僂儉/僼僃僯儖儃儘儞巁/悈宯偺昍忬儈僙儖偺挷惢
丒壓懞丂桳婸丄烴堜丂朑巕丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
儃儘儞巁巆婎傪2乫埵偵廋忺偟偨怴婯4-(僕儊僠儖傾儈僲)傾僝儀儞僛儞桿摫懱偺崌惉偲摐壔妛僙儞僒乕偲偟偰偺昡壙
丒壓懞丂桳婸丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丄弐挩
怴婯娷儂僂慺嶰娐宯崪奿傪桳偡傞寀岝惈摐壔妛僙儞僒乕
丒彫搰丂桾丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
僗儔僀僪儕儞僌壦嫶揰傪桳偡傞僎儖偵傛傞摐墳摎惈僶儖僽偺峔抸
丒晲堜丂愮栱丄彫搰丂桾丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
摐墳摎惈旝棻巕偺挷惢忦審偑栻暔曻弌惈偵媦傏偡塭嬁
丒娫丂桽懢楴丄慜愳丂弐媣丄Patel丂Avnish丄嶰栘丂椓懢榊丄戝搰丂怴巌丄峕愳丂桽嵠丄Lane丂Majella丄娭丂弐挩
僞僋儘儕儉僗擃峱嵻偺慡恎惈暃嶌梡偺夞旔傪栚揑偲偟偨旂晢撪媧廂摦懺偺専摙
丒Tomohiro Seki, Misato Namiki, Yuya Egawa, Ryotaro Miki, Kazuhiko Juni, Toshinobu Seki
Complexation of phenylboronic acid-modified polyethylene glycol with native 兞-cyclodextrin for sugar-responsive molecular necklace.
丒Tomohiro Seki, Keigo Abe, Yuya Egawa, Ryotaro Miki, Kazuhiko Juni, and Toshinobu Seki
Preparation of a sugar-responsive polypseudorotaxane having a directly sugar-binding sensor.
丒Yu Kojima, Yuya Egawa, Ryotaro Miki and Toshinobu Seki
Preparation of a sugar-responsive gel using rotaxane structures as cross-linkers.
丒彫搰 桾丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
壦嫶揰偵儘僞僉僒儞峔憿傪帩偪丄摐偵墳摎偟偰廂弅偡傞僎儖偺挷惢
丒慜愳 弐媣丄憹揷 桾峴丄娫 桽懢楴丄嶰栘 椓懢榊丄戝搰 怴巌丄峕愳 桽嵠丄娭 弐挩
旂晢揔梡屻偺僞僋儘儕儉僗偺慡恎媧廂傊偺寣娗廂弅嵻偺塭嬁
丒娭 抭岹丄暲栘 旤恗丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
僔僋儘僨僉僗僩儕儞偍傛傃崅暘巕嵔傊偺摐僙儞僒乕擇廳廋忺暘巕僱僢僋儗僗偺挷惢偲偦偺摐墳摎惈
丒暲栘 旤恗丄娭 抭岹丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
摐僙儞僒乕廋忺億儕僄僠儗儞僌儕僐乕儖傪梡偄偰挷惢偟偨暘巕僱僢僋儗僗偺摐墳摎惈偺儊僇僯僘儉偺挷嵏
丒壓懞 桳婸丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
儃儘儞巁巆婎傪桳偡傞僋儘僐僯儞桿摫懱偵傛傞寀岝摐壔妛僙儞僒乕偺峔憿夝愅
丒晲堜 愮栱丄彫搰 桾丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
儌僨儖僞儞僷僋幙栻傪娷桳偟偨摐墳摎惈旝棻巕偺挷惢
丒撪揷 榡丄娫 桽懢楴丄慜愳 弐媣丄嶰栘 椓懢榊丄峕愳 桽嵠丄娭 弐挩
僔僋儘僨僉僗僩儕儞偵傛傞僞僋儘儕儉僗偺旂晢撪摦懺惂屼偺帋傒
丒娫 桽懢楴丄Avnish PATEL丄Majella LANE丄娭 弐挩
僀僽僾儘僼僃儞旂晢揔梡屻偺旂晢摟夁惈偵媦傏偡揔梡惢嵻偺巆懚梕愊偺塭嬁
丒娭抭岹丄楅栘寬懢丄堜忋抦巕丄暲栘旤恗丄峕愳桽嵠丄嶰栘椓懢榊丄娭弐挩
摐僙儞僒乕暘巕廋忺偵傛傞僀儞僗儕儞偺摐墳摎惈寣拞堏峴惂屼偺帋傒
丒彫搰桾丄崅嫶戝庽丄峕愳桽嵠丄嶰栘椓懢榊丄娭弐挩
儘僞僉僒儞峔憿傪帩偮摐墳摎惈僎儖偺挷惢偲儌僨儖栻暔曻弌惈
丒Ryotaro Miki, Yasuna Ichitsuka, Soichiro Kimura, Yuya Egawa, Toshinobu Seki, Kazuhiko Juni, Hideo Ueda, Yasunori Morimoto
A membrane impregnated with a poly(dimethylsiloxane)/poly(ethylene glycol) copolymer for a high-throughput screening of the permeability of compounds across the human skin
丒彫搰 桾丄峕愳桽嵠丄嶰栘椓懢榊丄娭 弐挩
壦嫶揰偵儘僞僉僒儞峔憿傪桳偡傞摐偵墳摎偟偰朿弫偡傞僎儖偺挷惢
丒暲栘旤恗丄娭 抭岹丄峕愳桽嵠丄嶰栘椓懢榊丄娭 弐挩
摐僙儞僒乕廋忺億儕僄僠儗儞僌儕僐乕儖嵔傪幉惉暘偵梡偄偨僔僋儘僨僉僗僩儕儞暘巕僱僢僋儗僗偺挷惢
丒戝栰桼埶丄抾撪愮徎丄峕愳桽嵠丄嶰栘椓懢榊丄娭 弐挩
僕僺儕僕僯僂儉儃儘儞巁傪婎杮崪奿偲偟偨寀岝惈摐僙儞僒乕偺奐敪
丒慜愳弐媣丄娫桽懢楴丄嶰栘椓懢榊丄戝搰怴巌丄峕愳桽嵠丄娭 弐挩
旂晢旝彫弞娐偺曄壔偑僞僋儘儕儉僗宱旂媧廂摦懺偵媦傏偡塭嬁
丒崅嫶戝庽丄彫搰 桾丄峕愳桽嵠丄嶰栘椓懢榊丄娭 弐挩
僼僃僯儖儃儘儞巁廋忺僗儔僀僪儕儞僌僎儖偐傜偺儌僨儖栻暔曻弌惈昡壙
丒峕愳桽嵠丄娭抭岹丄垻晹孿屷丄嶰栘椓懢榊丄娭弐挩
摐壔妛僙儞僒乕廋忺億儕僔儏乕僪儘僞僉僒儞偺僀儞僗儕儞僨儕僶儕乕傊偺墳梡
丒娭抭岹丄垻晹孿屷丄峕愳桽嵠丄嶰栘椓懢榊丄娭弐挩
摐偲捈愙寢崌壜擻側僙儞僒乕廋忺婎傪桳偡傞摐墳摎PEG嵔曻弌億儕僔儏乕僪儘僞僉僒儞
丒壓懞桳婸丄娸岹庽丄峕愳桽嵠丄嶰栘椓懢榊丄娭弐挩
儃儘儞巁巆婎傪桳偡傞僋儘僐僯儞桿摫懱偵傛傞寀岝摐壔妛僙儞僒乕
丒峕愳桽嵠丄壓懞桳婸丄嶳岥宐巌丄埨惸弴堦
儃儘儞巁娷桳傾僝怓慺偵傛傞摐壔妛僙儞僒乕
丒娭抭岹 丄峕愳桽嵠 丄嶰栘椓懢榊 丄娭弐挩
摐僙儞僒乕廋忺僔僋儘僨僉僗僩儕儞暘巕僱僢僋儗僗傪梡偄偨僀儞僗儕儞曻弌惂屼
丒晲堜愮栱丄彫搰桽丄峕愳桾嵠丄嶰栘椓懢榊丄娭弐挩
儅僀僋儘儈僉僒乕梟弌帋尡婍傪梡偄偨僞儞僷僋栻偺摐墳摎惈曻弌偺昡壙
丒嶳岥 宐巌丄壓懞丂桳婸丄峕愳 桽嵠丄嶰栘 椓懢榊丄娭 弐挩
柍怓偐傜桳怓傊偺怓挷曄壔傪帵偡儃儘儞巁傪擇偮桳偡傞傾僝怓慺偵傛傞摐壔妛僙儞僒乕
丒垻晹 孿屷 丄娭抭岹 丄彫椦 桼婓 丄峕愳 桽嵠 丄嶰栘 椓懢榊丄娭 弐挩
摐墳摎惈億儕僔儏乕僪儘僞僉僒儞偺曵夡摿惈傊偺嵔挿偺塭嬁
丒娭 抭岹 丄峕愳 桽嵠 丄嶰栘 椓懢榊 丄娭 弐挩
摐僙儞僒乕壔妛廋忺暘巕僱僢僋儗僗偐傜偺PEG嵔曻弌偺摐墳摎惈夵慞偺帋傒
丒娫 桽懢楴 丄憹揷 桾峴 丄嶰栘 椓懢榊 丄戝搰 怴巌 丄峕愳 桽嵠 丄娭 弐挩
庬乆墛徢儌僨儖僿傾儗僗儔僢僩偵偍偗傞僞僋儘儕儉僗旂晢撪摦懺偺夝愅
丒彫椦 桼婓 丄娭 抭岹 丄峕愳 桽嵠 丄嶰栘 椓懢榊 丄娭 弐挩
DDS婎嵽偲偟偰棙梡壜擻側億儕僄僗僥儖-億儕僄乕僥儖嫟廳崌懱偺挷惢偲昡壙
丒嶰栘 椓懢榊 丄慜愳 弐媣 丄彑揷 桳婭 丄峕愳 桽嵠 丄娭 弐挩
暔棟揑巋寖偵傛傝曻弌惂屼偡傞昍忬儈僙儖悈梟塼偵娭偡傞専摙
丒怴堜 晳壴 丄嶰栘 椓懢榊 丄峕愳 桽嵠 丄娭 弐挩
擄梟惈壔崌暔偺梟夝惈夵慞傪栚揑偲偟偨儃僩儉傾僢僾朄偵傛傞旝棻巕偺挷惢
丒巗捤 桋嵷 丄嶰栘 椓懢榊 丄峕愳 桽嵠 丄娭 弐挩
僸僩旂晢摟夁惈梊應偺High throughput壔偵岦偗偨嫟廳崌懱娷怹枌偵娭偡傞専摙
丒壓懞 桳婸 丄娸 岹庽 丄峕愳 桽嵠 丄嶰栘 椓懢榊 丄娭 弐挩
旕峺慺揑側寣摐抣應掕傪栚巜偟偨嬤愒奜椞堟偱摐墳摎惈傪帵偡怓慺
丒楅栘 寬懢 丄娭 抭岹 丄嶰栘 椓懢榊 丄峕愳 桽嵠 丄娭 弐挩
僼僃僯儖儃儘儞巁廋忺僀儞僗儕儞偺儔僢僩旂壓搳梌屻偺媧廂偺昡壙
丒崱堜 彯旤 丄嶰栘 椓懢榊 丄峕愳 桽嵠 丄娭 弐挩
徚壔娗撪偺pH曄壔傪柾曧壜擻側in vitro 徚壔娗媧廂儌僨儖偺専摙
丒彫搰 桾 丄峕愳 桽嵠 丄嶰栘 椓懢榊 丄娭 弐挩
摐墳摎惈僗儔僀僪儕儞僌僎儖偐傜偺儌僨儖栻暔曻弌惈偺昡壙
丒撪揷 榡 丄峕愳 桽嵠 丄嶰栘 椓懢榊 丄娭 弐挩
寣摐抣埶懚宆梟夝惈偲暘嶶埨掕惈傪桳偡傞僀儞僗儕儞棻巕偺挷惢
丒堜忋 抦巕 丄娭 抭岹 丄嶰栘 椓懢榊 丄峕愳 桽嵠 丄娭 弐挩
僼僃僯儖儃儘儞巁廋忺僀儞僗儕儞偺摐寢崌摿惈偺挷嵏
丒晲堜 愮栱 丄媨尨 嵷惗 丄彫搰 桾 丄峕愳 桽嵠 丄嶰栘 椓懢榊 丄娭 弐挩
儌僨儖僞儞僷僋栻傪娷桳偟偨旝棻巕壔僎儖偺挷惢偲摐墳摎曻弌偺昡壙
丒壓懞丂桳婸丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
巼奜椞堟偐傜壜帇椞堟傊怓挷曄壔傪帵偡摐壔妛僙儞僒乕偺峔憿夝愅
丒娭丂抭岹丄堜忋丂抦巕丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
摐偵墳摎偟偰壦嫶偑愗抐偡傞僼僃僯儖儃儘儞巁廋忺僀儞僗儕儞暋崌懱偺挷惢
丒怴堜丂晳壴丄嶰栘丂椓懢榊丄峕愳丂桽嵠丄娭丂弐挩
旝棻巕壔偟偨擄梟惈壔崌暔偺梟夝惈偲偦傟偵媦傏偡悈梟惈崅暘巕偺塭嬁
丒垻晹丂孿屷丄娭丂抭岹丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
僼僃僯儖儃儘儞巁廋忺僔僋儘僨僉僗僩儕儞偲枛抂廋忺億儕僄僠儗儞僌儕僐乕儖偵傛傞億儕僔儏乕僪儘僞僉僒儞偺宍惉夁掱偺挷嵏
丒彫椦丂桼婓丄娭丂抭岹丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
僔僋儘僨僉僗僩儕儞偲崅暘巕偵傛傞億儕僔儏乕僪儘僞僉僒儞偺宍惉夁掱偺夝愅
丒彫搰丂桾丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
梲揹壸傪摫擖偟偨摐墳摎惈僗儔僀僪儕儞僌僎儖偵偍偗傞朿弫嫇摦偺昡壙
丒晲堜丂愮栱丄媨尨丂嵷惗丄彫搰丂桾丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
僕儃儘儞巁娷桳旝棻巕壔僎儖偐傜偺僞儞僷僋栻偺摐墳摎惈曻弌偺昡壙
丒娫丂桽懢楴丄嶰栘丂椓懢榊丄戝搰丂怴巌丄峕愳丂桽嵠丄娭丂弐挩
僞僋儘儕儉僗墛徢旂晢揔梡屻偺妏憌僶儕傾擻媦傃旂撪忬懺偵埶懚偟偨媧廂摦懺偺夝愅
丒娫丂桽懢楴, 憹揷丂桾峴, 嶰栘丂椓懢榊, 峕愳丂桽嵠, 娭丂弐挩
儅僀僋儘僟僀傾儕僔僗傪梡偄偨僞僋儘儕儉僗旂晢揔梡屻偺旂晢撪摦懺夝愅朄偺専摙
丒垻晹丂孿屷丆娭 抭岹丆峕愳丂桽嵠丆嶰栘丂椓懢榊丆娭 弐挩
廋忺僔僋儘僨僉僗僩儕儞傪梡偄偨摐墳摎惈挻暘巕暋崌懱偺挷惢偲僀儞僗儕儞曻弌惂屼傊偺墳梡
丒憹揷丂桾峴丆娫丂桽懢楴丆嵅摗丂戦栫丆嶰栘丂椓懢榊丆戝搰丂怴巌丆峕愳丂桽嵠丆娭 弐挩
墛徢旂晢偵偍偗傞寣娗奜傊偺僞儞僷僋幙偺楻弌偲偦偺栻暔宱旂媧廂摦懺傊偺塭嬁
丒娭 抭岹 丄峕愳丂桽嵠 丄嶰栘 椓懢榊 丄娭 弐挩
僼僃僯儖儃儘儞巁廋忺 兞-僔僋儘僨僉僗僩儕儞傪梡偄偨堦杮嵔億儕僔儏乕僪儘僞僉僒儞偺挷惢偲摐擹搙偵墳偠偨
PEG 嵔儕儕乕僗嫇摦
丒彫搰丂桾丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
僼僃僯儖儃儘儞巁亅僩儕僆乕儖偺寢崌偲偦偺夝棧傪棙梡偟偨摐墳摎惈僗儔僀僪儞僌僎儖偺挷惢偲昡壙
丒娫丂桽懢楴丄憹揷丂桾峴丄栁栘丂戱栫丄嶰栘丂椓懢榊丄峕愳丂桽嵠丄娭丂弐挩
僞僋儘儕儉僗慖戰揑旂撪憲払偺偨傔偺婎慴揑尋媶
丒撪揷丂榡丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
僀儞僗儕儞偲僕儃儘儞巁桿摫懱偺嫟捑揳偵傛傝惗偠傞棻巕偺摐墳摎惈僀儞僗儕儞曻弌
丒嶰栘丂椓懢榊丄愺崄丂抦巕丄壀揷丂峴旻丄峕愳丂桽嵠丄娭丂弐挩
梟弌乗媧廂夁掱傪楢懕揑偵昡壙偡傞in vitro徚壔娗媧廂儌僨儖偵娭偡傞専摙乗嵻宍娫偺斾妑乗
丒晲堜丂愮栱丄媨尨丂嵷惗丄彫搰丂桾丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
儅僀僋儘儈僉僒乕宆梟弌帋尡婍傪梡偄偨僕儃儘儞巁娷桳旝棻巕壔僎儖偺僌儖僐乕僗墳摎惈偺昡壙
丒峕愳丂桽嵠丄娭丂弐挩
摐墳摎惈僀儞僗儕儞儕儕乕僗僔僗僥儉傪巜岦偟偨挻暘巕僫僲儅僔儞乮僔儞億僕僂儉乯
丒嶰栘丂椓懢榊丄拞懞丂桟巕丄壀揷丂峴旻丄峕愳丂桽嵠丄娭丂弐挩
栻暔偺梟弌乗媧廂夁掱傪楢懕揑偵挷嵏壜擻側in vitro徚壔娗媧廂儌僨儖嶌惉偵岦偗偨婎慴揑専摙
丒娭丂抭岹丄嶰栘丂椓懢榊丄峕愳丂桽嵠丄娭丂弐挩
枛抂僫僼僩僀儖婎廋忺PEG壔僀儞僗儕儞偺妶惈昡壙偲in situ僔僋儘僨僉僗僩儕儞暘巕僱僢僋儗僗宍惉偺専摙
丒娫丂桽懢楴丄嵅摗丂戦栫丄嶰栘丂椓懢榊丄戝搰丂怴巌丄峕愳丂桽嵠丄娭丂弐挩
僿傾儗僗儔僢僩墛徢旂晢偵偍偗傞擃峱揾晍屻偺僞僋儘儕儉僗媧廂摦懺
丒彫搰丂桾丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
僼僃僯儖儃儘儞巁廋忺摐墳摎惈僗儔僀僪儕儞僌僎儖偺挷惢偲昡壙
丒壓懞丂桳婸丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄埨惸丂弴堦丄娭丂弐挩
懡妀NMR偵傛傞僕儃儘儞巁傾僝怓慺偺摐墳摎惈儊僇僯僘儉偺挷嵏
丒撪揷丂榡丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
僼僃僯儗儞僕儃儘儞巁偲儁儞僞僄儕僗儕僩乕儖娫偺憡屳嶌梡偵傛傝惗偠傞崅暘巕儅僀僋儘僷乕僥傿僋儖偺摐墳摎惈偺挷嵏
丒抾撪丂愮徎丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
僕僀僜僉僲儕僯僂儉儃儘儞巁傪梡偄偨寀岝惈僌儖僐乕僗僙儞僒乕
丒崺晍扟丂婌惉丄彫椦丂曭暥丄墶堜丂戝庽丄嶰栘丂椓懢榊丄峕愳丂桽嵠丄娭丂弐挩
擲枌忋旂憌忋偺忬嫷傪憐掕偟偨曻弌幚尡宯偵娭偡傞婎慴揑尋媶
丒媨尨丂嵷惗丄愒塇崻丂嵷捗巕丄堜庤丂払栫丄弌塝丂惓婱丄嶰栘丂椓懢榊丄峕愳丂桽嵠丄娭丂弐挩
惗棟揑忦審壓偱揹婥壔妛墳摎傪帵偡僕儃儘儞巁-僇僥僐乕儖僔僗僥儉僌儖僐乕僗僙儞僒乕
丒晲堜丂愮栱丄媨尨丂嵷惗丄彫搰丂桾丄峕愳丂桽嵠丄嶰栘丂椓懢榊丄娭丂弐挩
僕儃儘儞巁偲億儕價僯儖傾儖僐乕儖偐傜惉傞僌儖僐乕僗墳摎惈旝棻巕壔僎儖
丒悰揷丂桾擇丄彫揷丂宑婌丄峕愳丂桽嵠丄娭丂弐挩丄椤扟丂梫丄嶳僲堜丂岶
兛-N-傾僙僠儖僌儖僐僒儈儞巆婎廤愊宆僨儞僪儕儅乕偺崌惉偲峈僺儘儕嬠妶惈
丒峕愳丂桽嵠
寣摐抣墳摎惈僀儞僗儕儞儕儕乕僗婎嵻偲偟偰偺僔僋儘僨僉僗僩儕儞桿摫懱挻暘巕
丒彫搰丂桾丄峕愳丂桽嵠丄娭丂弐挩
僼僃僯儖儃儘儞巁傪梡偄偨摐墳摎惈僗儔僀僪儕儞僌僎儖偺挷惢偲昡壙
丒娭丂抭岹丄峕愳丂桽嵠丄娭丂弐挩
摐墳摎惈暘巕僱僢僋儗僗傪梡偄偨僀儞僗儕儞僨儕僶儕乕
丒峕愳丂桽嵠丄娭丂抭岹丄拞懞丂岞孫丄彫揷丂宑婌丄嶳僲堜丂岶丄娭丂弐挩
僼僃僯儖儃儘儞巁廋忺僔僋儘僨僉僗僩儕儞偵傛傞挻暘巕峔憿宍惉偲偦偺摐墳摎惈
丒壓懞丂桳婸丄峕愳丂桽嵠丄娭丂弐挩
峀堟斖埻偺pH偱挿攇挿曄壔傪帵偡摐墳摎惈僕儃儘儞巁廋忺傾僝怓慺
丒娭丂抭岹丄峕愳丂桽嵠丄拞懞丂岞孫丄彫揷丂宑婌丄嶳僲堜丂岶丄娭丂弐挩
寣摐抣墳摎惈僀儞僗儕儞僨儕僶儕乕婎嵻偲偟偰偺僔僋儘僨僉僗僩儕儞桿摫懱挻暘巕
丒娭丂弐挩
僀儞僗儕儞偺宱旲僨儕僶儕乕偵娭偡傞婎慴揑尋媶乮僔儞億僕僂儉乯
丒壓懞丂桳婸丄峕愳丂桽嵠丄娭丂弐挩
峀斖埻偺pH偱摐墳摎惈傪帵偡儃儘儞巁廋忺傾僝怓慺偺崌惉
丒娭丂抭岹丄峕愳丂桽嵠丄拞懞丂岞孫丄娭丂弐挩
僼僃僯儖儃儘儞巁廋忺僔僋儘僨僉僗僩儕儞偲億儕僄僠儗儞僌儕僐乕儖偵傛傝宍惉偝傟傞摐墳摎惈挻暘巕僱僢僋儗僗偺峔憿夝愅
丒楅栘丂愮恞丄峕愳丂桽嵠丄戝搰丂怴巌丄嵶扟丂帯丄渘擇丂榓旻丄娭丂弐挩
恖岺枌愊憌偲儅僀僋儘僟僀傾儕僔僗傪慻傒崌傢偣偨旂晢儌僨儖幚尡宯偺昡壙
丒郷揷丂垽棦丄栘撪丂婱復丄峕愳丂桽嵠丄撪揷丂徆婓丄栘懞丂憦堦榊丄
忋揷丂廏梇丄壞栚丂廏帇丄怷杮 璐寷丄娭丂弐挩
忋旂嵶朎扨憌枌儌僨儖偺嵶朎娫寗摟夁惈昡壙偺偨傔偺幚尡宯偺専摙
丒拞懞丂岞孫丄峕愳丂桽嵠丄娭抭丂岹丄彫揷丂宑婌丄嶳僲堜丂岶丄娭丂弐挩
僼僃僯儖儃儘儞巁廋忺僔僋儘僨僉僗僩儕儞偺暘巕娫曪愙傪棙梡偟偨摐墳摎惈挻暘巕億儕儅乕偺峔憿夝愅
丒彫搰丂桾丄峕愳丂桽嵠丄娭丂弐挩
僼僃僯儖儃儘儞巁廋忺僗儔僀僪儕儞僌僎儖偺挷惢偲摐墳摎惈偺昡壙
丒嵅摗丂戦栫丄栘撪丂婱復丄峕愳丂桽嵠丄戝搰丂怴巌丄嵶扟丂帯丄渘擇丂榓旻丄娭丂弐挩
墛徢傪桳偡傞旂晢偵偍偗傞僞僋儘儕儉僗偺媧廂摦懺偵娭偡傞婎慴揑尋媶
丒嵅摗丂戦栫丄楅栘丂愮恞丄栘撪丂婱復丄峕愳丂桽嵠丄戝搰丂怴巌丄嵶扟丂帯丄渘擇丂榓旻丄娭 弐挩
旂晢撪偵偍偗傞僞僋儘儕儉僗偺堏摦摦懺偵娭偡傞婎慴揑尋媶
丒娭丂抭岹丄峕愳丂桽嵠丄拞懞丂岞孫丄娭丂弐挩
僼僃僯儖儃儘儞巁廋忺僔僋儘僨僉僗僩儕儞傪梡偄偨摐懚嵼壓偱曵夡偡傞億儕僔儏乕僪儘僞僉僒儞偺挷惢
丒拞懞丂岞孫丄 峕愳丂桽嵠丄 娭丂抭岹丄 娭丂弐挩
僼僃僯儖儃儘儞巁廋忺僔僋儘僨僉僗僩儕儞偺崌惉偲偦偺暘巕娫憡屳嶌梡偵傛傞摐墳摎惈挻暘巕億儕儅乕偺宍惉
丒嶳壓丂旤婭丄戝搰丂怴巌丄嵶扟丂帯丄峕愳丂桽嵠丄娭丂弐挩丄渘擇丂榓旻
僔僋儘僨僉僗僩儕儞儅僀僋儘僗僼傿傾偺挷惢偲偦偺暘巕峔憿偺夝愅
丒拞懞丂岞孫丄峕愳丂桽嵠丄娭丂抭岹丄娭丂弐挩
僔僋儘僨僉僗僩儕儞偲僼僃僯儖儃儘儞巁偺憡屳嶌梡傪棙梡偟偨摐墳摎惈挻暘巕億儕儅乕
丒娭丂抭岹丄峕愳丂桽嵠丄拞懞丂岞孫丄娭丂弐挩
僼僃僯儖儃儘儞巁廋忺僔僋儘僨僉僗僩儕儞傪梡偄偨摐墳摎惈億儕僔儏乕僪儘僞僉僒儞偺挷惢
丒郷揷丂垽棦丄栘撪丂婱復丄峕愳丂桽嵠丄栘懞丂憦堦榊丄忋揷丂廏梇丄怷杮丂璐寷丄娭丂弐挩
忋旂嵶朎扨憌枌偺嵶朎娫寗摟夁宱楬偺昡壙傪栚揑偲偟偨幚尡宯偺専摙
丒嵅摗丂戦栫丄楅栘 愮恞丄栘撪丂婱復丄峕愳丂桽嵠丄戝搰丂怴巌丄嵶扟丂帯丄渘擇丂榓旻丄娭 弐挩
旂晢撪偵偍偗傞僞僋儘儕儉僗偺堏摦摦懺偵娭偡傞婎慴揑尋媶
丒楅栘 愮恞丄嵅摗丂戦栫丄峕愳丂桽嵠丄戝搰丂怴巌丄嵶扟丂帯丄渘擇丂榓旻丄娭丂弐挩
恖岺枌愊憌偲儅僀僋儘僟僀傾儕僔僗傪慻傒崌傢偣偨旂晢儌僨儖幚尡宯偺昡壙
丒拞懞丂岞孫丄峕愳丂桽嵠丄娭丂抭岹丄娭丂弐挩
僼僃僯儖儃儘儞巁廋忺僔僋儘僨僉僗僩儕儞偵傛傞摐墳摎惈挻暘巕億儕儅乕偺奐敪
丒郷揷丂垽棦丄栘撪丂婱復丄峕愳丂桽嵠丄忋揷丂廏梇丄怷杮丂璐寷丄娭丂弐挩
忋旂嵶朎扨憌枌儌僨儖偺嵶朎娫寗摟夁惈昡壙偺偨傔偺幚尡宯偺専摙
丒嵵摗丂梲夘丄惔悈丂桽婓丄娭丂抭岹丄峕愳丂桽嵠丄娭丂弐挩
擲枌揔梡偺偨傔偺PEG壔僀儞僗儕儞偺崌惉偲昡壙
丒惔悈丂桽婓丄嵵摗丂梲夘丄峕愳丂桽嵠丄娭丂弐挩
億儕僀僆儞暋崌懱傪棙梡偟偨僀儞僗儕儞憲払偵娭偡傞婎慴揑尋媶
丒娭丂抭岹丄峕愳丂桽嵠丄拞懞丂岞孫丄娭丂弐挩
僼僃僯儖儃儘儞巁廋忺僔僋儘僨僉僗僩儕儞傪梡偄偨摐墳摎惈暘巕僱僢僋儗僗偺挷惢
丒彫搰丂桾丄峕愳丂桽嵠丄娭丂弐挩
僼僃僯儖儃儘儞巁桿摫懱偲億儕價僯儖傾儖僐乕儖偐傜惉傞摐墳摎惈儅僀僋儘僗僼傿傾偺挷惢
丒栘撪丂婱復丄娭丂弐挩丄悾屗丂岹庽丄忋揷丂廏梇丄峕愳丂桽嵠丄栘懞丂憦堦榊丄怷杮丂璐寷
旂晢偵偍偗傞悈岴宱楬傪夘偡傞崅暘巕栻暔偺媧廂惈偺昡壙偺偨傔偺幚尡宯偵娭偡傞専摙
丒嶳揷丂岻幚丄嶰栘丂椓懢榊丄栘懞丂憦堦榊丄娭丂弐挩丄忋揷丂廏梇丄怷杮丂璐寷
In vitro旂晢摟夁帋尡偺偨傔偺僸僩旂晢戙懼恖岺枌偵岦偗偨PDMS/PEG嫟廳崌懱娷怹枌偵娭偡傞専摙 (1)
乗恊悈惈宱楬偺嵶岴僷儔儊乕僞偺昡壙乗
丒嶰栘丂椓懢榊丄嶳揷丂岻幚丄栘懞丂憦堦榊丄娭丂弐挩丄渘擇丂榓旻丄忋揷丂廏梇丄怷杮丂璐寷
In vitro旂晢摟夁帋尡偺偨傔偺僸僩旂晢戙懼恖岺枌偵岦偗偨PDMS/PEG嫟廳崌懱娷怹枌偵娭偡傞専摙 (2)
乗働僩僾儘僼僃儞偺暘巕宍偍傛傃僀僆儞宍偺摟夁惈乗
丒戝搰丂怴巌丄殸堜丂朁崄丄戧揷丂朁壛丄揷拞丂嫕丄嵶扟丂帯丄娭丂弐挩丄渘擇丂榓旻
兝-lactoglobulin 偵傛傞Indomethacin 婲場惈彫挵忈奞儔僢僩偺彫挵擲枌僶儕傾擻偺夞暅
丒戝懞丂桭悞丄捪丂宑堦丄杒懞丂恀堦丄晲摗丂崄奊丄栘懞丂憦堦榊丄娭丂弐挩丄忋揷丂廏梇丄怷杮丂璐寷
Renkin幃傪梡偄偨掅廃攇悢挻壒攇偺妏幙憌僶儕傾傊偺塭嬁偵娭偡傞専摙
丒楅栘丂愮恞丄巜揷丂払栫丄戝搰丂怴巌丄峕愳丂桽嵠丄渘擇丂榓旻丄娭丂弐挩
栻暔旂晢揔梡屻偺旂晢撪摦懺夝愅偺偨傔偺儅僀僋儘僟僀傾儕僔僗偺棙梡丄儅僀僋儘僟僀傾儕僔僗尋媶夛
丒愇堜丂払栫丄饫搰丂棽恗丄戝搰丂怴巌丄峕愳丂桽嵠丄嵶扟丂帯丄娭丂弐挩丄渘擇丂榓旻
Polypropylene glycol 傪暘嶶攠偲偟偰梡偄傞婡擻惈崅暘巕儅僀僋儘僗僼傿傾偺挷惢
丒戝墇丂梇堦榊丄杒懞丂恀堦丄娭丂弐挩丄栘撪丂婱復丄峕愳丂桽嵠丄拞愳丂峅巕丄栘懞丂憦堦榊丄忋揷丂廏梇丄怷杮丂璐寷
帺揮丒岞揮儈僉僒乕傪梡偄偰挷惢偟偨擕嵻偺埨掕惈偵懳偡傞庬乆奅柺妶惈嵻偺塭嬁
丒桍懞丂梲巕丄摗摪丂峗柧丄娭丂弐挩丄悪椦丂寴師
旝棻巕傪梡偄偨栻暔宱旂媧廂懀恑岠壥
丒揷奓丂棾堦丄栘懞丂憦堦榊丄忋揷丂廏梇丄娭丂弐挩丄怷杮丂璐寷丄
EUDRAGITR E 傪梡偄偨旂晢揔梡偵揔偟偨擲拝惈婎嵻挷惢偵娭偡傞婎慴専摙
丒恵摗丂柧惗丄捪丂宑堦丄晲摗丂崄奊丄栘懞丂憦堦榊丄娭丂弐挩丄忋揷丂廏梇丄怷杮丂璐寷
掅廃攇悢sonophoresis偵偍偗傞挻壒攇廃攇悢埶懚揑岠壥偺専摙
丒栘撪丂婱復丄娭丂弐挩丄忋揷丂廏梇丄峕愳丂桽嵠丄拞愳丂峅巕丄栘懞丂憦堦榊丄怷杮丂璐寷
懡岴枌偺栻暔摟夁惈偺昡壙偺偨傔偺幚尡宯偵娭偡傞専摙
丒巜揷丂払栫丄戝搰丂怴巌丄峕愳丂桽嵠丄嵶扟丂帯丄娭丂弐挩丄渘擇丂榓旻
枌愊憌宆旂晢儌僨儖傪梡偄偨栻暔摟夁偵懳偡傞傾儖僽儈儞偺塭嬁昡壙
丒峕愳丂桽嵠丄揷拞丂岲岾丄屻摗丂椙懢丄怴柤丂惞丄拞愳丂峅巕丄娭丂弐挩丄埨惸丂弴堦
B-N 憡屳嶌梡傪尞偲偡傞怓挷曄壔摐僙儞僒乕壔崌暔偺15N NMR 暘岝偲検巕壔妛寁嶼
丒幝尨丂崕揟丄郪揷丂桞旤丄戝栴丂抭懃丄尨堜丂尗廏丄娭丂弐挩丄娸栰丂嫓
媬柦媬媫僙儞僞乕偵偍偗傞栻嵻娗棟巜摫嬈柋幚巤偵塭嬁傪媦傏偡梫場偺夝愅
丒戝墇丂梇堦榊丄杒懞丂恀堦丄娭丂弐挩丄栘撪丂婱復丄峕愳丂桽嵠丄拞愳丂峅巕丄栘懞丂憦堦榊丄忋揷丂廏梇丄怷杮丂璐寷
帺揮丒岞揮儈僉僒乕傪梡偄偨擕嵻偺挷惢偵娭偡傞婎慴揑尋媶
丒栘撪丂婱復丄娭丂弐挩丄忋揷丂廏梇丄峕愳丂桽嵠丄拞愳丂峅巕丄栘懞丂憦堦榊丄怷杮丂璐寷
僐儘僫壸揹壔棻巕専弌婍乮CAD乯傪梡偄偨摐椶偺摨帪掕検朄偺専摙偍傛傃枌摟夁惈昡壙傊偺揔梡
丒娭丂弐挩
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